I tried the thiamine and magnesium combo and I do think it helped, but the efficacy/half-life wore off quicker and quicker, so I had to up my dosage every two weeks and that wasn't sustainable. I also noticed as soon as it would wear off and it was time to take the next dose, my speech became worse than it ever was, and I'd panic to get the next dose in. Eventually I decided to quit because it wasn't sustainable and for a few weeks after I stopped, my speech was worse than when I started and then it slowly started to even back out over the next few months.