Tried a few medications, including drugs within two years. (Thiamin, Olanzapine, GABA, Vitamine complex and other drugs) Nothing has helped. Just felt the side effects like extreme fatigue, lack of concentration and rapid weight gain. My stutter is severe. My stutter is blocking only, but heavy blocks... I am still waiting for the actual studies. Emalex Bioscience Ecopipam and Noema Pharma [https://noemapharma.com/2022/08/04/noema-pharma-announces-recruitment-of-first-patient-in-orpheus-phase-2b-study-of-pde10a-inhibitor-gemlapodect-in-adults-with-childhood-onset-fluency-disorder/](https://noemapharma.com/2022/08/04/noema-pharma-announces-recruitment-of-first-patient-in-orpheus-phase-2b-study-of-pde10a-inhibitor-gemlapodect-in-adults-with-childhood-onset-fluency-disorder/) The free availability of these drugs will not happen before 2025.... :/ Every day I look in google what news there is about stuttering... nothing... I think it is a pity that so little research is done. After all, it affects 1% of the world's population.