Just to add a bit more info: There have been multiple small medication trials over the years, and one larger one (pagaclone) in the mid 2000s. None of them have shown efficacy, but the results of pagaclone were looking promising (from what I've heard...) but the pharmaceutical company dropped it for financial reasons. More personally, I have close friends who participated in that trial who really liked taking the drug and felt that it helped, but when the medication was pulled b/c the study stoped, experienced a hard crash and was severely debilitated in how easy it was for them to speak or even engage in life.